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Synthesis and Aplication of Some New 5-Sulphonyl-N-Heterocyclo-8-Hydroxyquinoline Derivatives as Potential Drugs

Research Authors
Ali A.Abdel Hafez and Ibrahim M.A.Awad
Research Abstract

Some new sulphonyl-N-heterocyclo-8-hydroxy quinolines have been synthesised by the reaction of 8-hydroxyquinoline-5-sulphonyl hydrazide with different active methylene compounds. The pyrazole, pyrazoline, pyrazolidine and pyridazine derivatives were reacted with some metal cations to give the corresponding chelates. All synthesized compounds have been screened in vitro for their biological activities

Research Department
Research Journal
Phosphorus, Sulfer and Silicon
Research Member
Research Rank
2
Research Vol
Vol. 61, No 3-4
Research Year
1991
Research Pages
pp. 381 - 389