A buffalo bull was presented to the college hospital with the complaint of the presence of a huge swelling. The animal had been infected with edematous skin disease for three months. The abscess was diagnosed as the presence of large swelling, exploratory puncture, radiographically and by ultrasongraphy. This huge abscess was removed by surgical excision under the effect of sedation and local analgesia. No postoperative complications were observed during a four-month follow up period. The abscess was successfully removed by surgical excision, which resulted in better aesthesis and an increase in the marketability of the animal.