Berry skin of Red grape, content and composition of pectin, anthocyanin and phenolic compounds development were evaluated in two Red cultivars (Beauty and Muscat Alex) from veraison to ripening with foliar spray by CaCl2 at 6% concentration on (2013- 2014 ) seasons. The results showed that the amount of anthocyanin and total phenolics in grape skin samples increased in ripening stage but pectin decreased. While berries treated by CaCl2 had a higher values of pectin than untreated berries in ripening stage of two seasons. Statistically significant difference were founded between the cultivars (P<0.05 ) Phenolic acids fractionations by HLPC was showed that the highest value was registered Salicylic in veraison stage, caffeine in ripening stage and Cinnamic in berries treated by CaCl2 in  ripening stage of Beauty cultivar .Along Protocatechuic and salicylic were recorded in veraison stage, Caffeine and Vanillic in ripening stage and Cinnamic in ripening stage of berries treated by CaCl2 of Muscat Alex cultivar among other phenolic acids quantified . After that phenolic composition is highly diversified among different development stage and varieties.   

Key words:-    Red cultivars (Beauty and Muscat Alex),  veraison , HLPC, polyphenol compounds.