Abstract Robotic surgery is one of the most recent technologies in healthcare building field. Due to the design complexity of Robotic surgery wards, computational implementations are being developed to either measure the effect of inserting advanced technologies as Electronic medical recorders and tele surgery, or evaluate design alternatives on health-care building. This paper presents a design framework that responds to the need for coordinating design phases for Robotic Surgery Wards (RSWs) computationally. This proposed design framework for RSWs can generate functional RSW alternatives and more than one solution for each alternative. The framework has been structured based on the main architectural considerations of RSWs which are geometric and topological, the economic considerations, specific developed pools for shape and corridor patterns, and the theory of “Shape Grammars"has been utilized to compute the framework to generate a vast number of design alternatives. Accordingly, a computational implementation has been established to assist designers in early design stages. Numerical validation for the applications of the developed framework and implementation has been conducted by using reference examples of RSWs. The main finding in this paper is providing healthcare building designers with a computational implementation that generates RSW alternative computationally based on specific shape and cost levels.