the incidance of bladder cancer is rising throughout the world ,the study results : Male seven times affected more than female with age distribution 30-91 year, half of cases were smoker ,and bilharzias in 27.8%.most cases were transitional cell carcinoma TCC 59/97 cases , mainly high grade in 62.7% followed by squamous cell carcinoma SCC 26/97, mainly moderate grade 53.9%. Non muscle invasive bladder cancer NMIBC constituted 8.2%, muscle invasive bladder cancer MIBC constituted 76.3%. Treatment response were assed in 77 cases , NMIBC 5 cases treated by transurethral resection followed by intravesical docetaxel CR in 80% cases.MIBC treated by: chemo-radiation in 26 cases with complete response in50%,radical ctectomy in 23 cases with CR in 69.6%, or by partial cyctectomy in 6 cases with 50% complete response. Conclusion: TCC is the most common pathology followed by SCC ,smoking is the main risk factor ,flowed by bilharziasis