Skip to main content

Intraoperative Radiotherapy promoting early Breast Cancer Detection: An observational

Research Authors
Maha Abdel Hadi, Lina Abu Arida, Amal Khalifa, Hiyam Al Haddad
Research Date
Research Member
Research Website
https://www.researchgate.net/profile/Maha-Abdelhadi/publication/320465637_The_impact_of_Intraoperative_Radiotherapy_on_breast_cancer_early_detection_An_Observational_Review/links/59e6e91d4585151e54601f30/The-impact-of-Intraoperative-Radiotherapy-on-breast
Research Year
2017
Research Abstract

Aim: The lack of structured breast cancer awareness programs (BCAP) in developing countries coupled by the scarcity of radiation oncology centers limit the available surgical options. The aim of this study is to Probe the use Intraoperative radiotherapy (IORT) treatment as a stem to initiate positive impact on early disease detection and propagate breast conserving surgery (BCS).

Materials and Methods: This observational review was undertaken at King Fahd hospital of the university, AL Khobar, Eastern province of Saudi Arabia between 2012-2016. All patients diagnosed with breast cancer were reviewed. Strict recruitment criteria were adopted for patients to receive IORT. Selected candidates where only those who were eligible and consented to undergo BCS and IORT. Special emphasis was placed on demographic data, tumor size at the initial presentation, post Neo-adjuvant chemotherapy response, post–pathology cavity size and applicator size used.

Results: The total number of patients diagnosed with breast cancer were 330 out of which 69 (20%) patient were eligible for IORT. Age ranged from31-75years with the Median age 50 years. Applicator sizes used ranged from 2.0-5.0. Tumor size ranged between 0.6-4.0 centimeters. 1 (1%) was post pathology case with excision performed two weeks prior to presentation. 0-1 in 8 (11%), 1.1-2 in 22 (31%), 2.1-3 in 24 (34%), and 3.1-4.0 in 15 (21%) patients. 7 (10%) patients received Neo-adjuvant chemotherapy with positive response and were included. The applicator sizes available ranged between 1.5-5.0 centimeters. Applicator sizes were size 2.0 in 2 (3%), size 2.5 in 10 (14%), size 3.0 in 18 …