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Department of Pharmaceutical Analytical Chemistry

Research

Our research spans a wide range from basic chemical, analytical, and pharmaceutical studies. Much of this research is focused on three strategic Research Themes:

Pharmaceutical analysis and quality control - Analysis of drugs in biological fluids and - Environmental monitoring.

Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones, analysis of drugs and compounds of pharmaceutical interest in pure form and in different formulations with the best possible sensitivity, accuracy and precision. Moreover, the basic and advanced studies that are done in the field of biological fluid analysis and environmental matrices.

The Department has major national and international collaborative research projects and a significant output of research publications in high-ranking journals (More than 400 publications up to 2010). Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
1 Development of an innovative turn-on fluorescent probe for targeted in-vivo detection of nitric oxide in rat brain extracts as a biomarker for migraine disease 2024
2 Spectrofluorimetric determination of Alogliptin benzoate through condensation with ninhydrin and phenylacetaldehyde: application to dosage form and rat plasma 2024
3 A surfactant-based quasi-hydrophobic deep eutectic solvent for dispersive liquid-liquid microextraction of gliflozins from environmental water samples using UHPLC/fluorescence detection 2024
4 Zirconium-based hydrophobic-MOFs as innovative electrode modifiers for flibanserin determination: Exploring the electrooxidation mechanism using a comprehensive spectroelectrochemical study 2024
5 Bifunctional Fe(III) metal-organic framework: A highly sensitive “turn-off” fluorescent probe and a precursor of magnetite nanoparticles for potential water decontamination 2023
6 A novel mesna-based electrochemical sensor embellished with silver nanoparticles for ultrasensitive analysis of modafinil Human Plasma 2023
7 A feasible HPTLC method for concurrent quantitation of allopurinol-montelukast co-therapy in plasma and evaluation of their hepatic and renal effects in rats: Analytical, biochemical, and histopathological study 2023
8 Polypyrrole/carbon dot nanocomposite as an electrochemical biosensor for liquid biopsy analysis of tryptophan in the human serum of normal and breast cancer women 2023
9 Combined Experimental/Computational Aspects for the Molecular Interaction of Empagliflozin with Bovine Serum Albumin: Quantification, and Application to Human Plasma 2023
10 NiFe‑based Prussian blue analogue nanopolygons hybridized with functionalized glyoxal polymer as a voltammetric platform for the determination of amisulpride in biological samples 2023