Worldwide, stored products are attacked by a large number of pests resulting in significant economic losses. Among these stored grain pests, khapra beetle, Trogoderma granarium (Everts) (Coleoptera: Dermestidae) is one of the top ranked pests that has ability to survive under diverse climate conditions. The management of this pest is mainly done by using synthetic chemicals which have side effects on consumers, ecosystem and non-target organisms. However, phyto-derivatives were found to be the effective environment friendly alternatives against T. granarium. Therefore, in this review, success of phyto-derivatives against khapra beetle from conventional means to modern research has been critically analyzed, summarized and discussed. In context, the different life stages of the insect starting from egg laying to adult development have been briefly explained. The review focuses upon recent research conducted on the evaluation of dozens of phyto-derivatives. In addition, the article has also highlighted some limitations of plant derived compounds and concludes via hoping that the future formulated pesticides will be safer, economical, least toxic to human and our planet ecosystem.