Urinary nephrin and alpha one microglobulin as early renal injury biomarkers in patients with
inflammatory bowel disease Section A -Research paper
Eur. Chem. Bull. 2023,12(Special issue 8),8616-8627 8616
Urinary nephrin and alpha one microglobulin as early renal
injury biomarkers in patients with inflammatory bowel
disease
Wael A Abbas1, Zeinab A Abdelhameed2, Noha G Abdelmalik1, Mohamed A
Tohamy1, Hosam M Abdelwahab1
1 Department of Internal Medicine, Assiut University Hospital, Assuit University
2 Department of Clinical Pathology, Assiut University Hospital, Assuit University
Received:3-7-2023 Accepted:30-7-2023 Published:31-7-2023
Abstract
Background& aim: Inflammatory bowel disease is an idiopathic disease characterized
by severe inflammation of the gastrointestinal tract. Renal affection could occur in 4%-
23% of patients with inflammatory bowel disease. The study aimed to assess role of
urinary nephrin and alpha one microglobulin as early renal injury biomarkers in patients
with inflammatory bowel disease
Patients& Methods: In this study, a total of 90 patients with inflammatory bowel disease
were enrolled. All patients were subjected to full history and clinical evaluation with
baseline laboratory data. In addition to, urinary nephrin and urinary α 1microglobulin
were measured.