Serum periostin and eotaxin-2 as promising biomarkers in asthmatic smokers

Faculty of Medicine

Assiut University

Serum periostin and eotaxin-2 as promising biomarkers in asthmatic smokers

Research Authors
Saher Farghly, Atef Farouk El-Karn, Mahmoud Farouk Sherif, Mohamed Ismail Seddik, Safaa Abdelgayed, Mohammed Abdelghany
Research Date
Research Department
Department of Clinical Pathology
Research Journal
European Respiratory Journal
Research Member
Mohamed Ismail Sedeek
Research Publisher
European Respiratory Society
Research Vol
Volume 58, Issue suppl 65
Research Website
https://scholar.google.com.eg/scholar?oi=bibs&cluster=1349779105894807514&btnI=1&hl=en
Research Year
2021
Research Abstract

Serum periostin and eotaxin-2 as promising biomarkers in asthmatic smokers.

Background: Smoking influence many changes in asthmatic airway inflammation by stimulating the production of certain cytokines. Serum periostin and eotaxin-2 in asthmatic patients are affected by smoking.

Objectives: The purpose of this study was to study serum periostin and eotaxin-2 level in asthmatic smokers.

Patients and methods: The present observational, cross sectional study was conducted at Chest department in Assiut university hospital, during the period from August 2018 to January 2020. Hundred and seventeen asthmatic patients (42 smokers, 30 ex-smokers and 45 non-smokers) were studied for serum periostin and eotaxin-2 (ELISA). The effects of smoking status and inflammatory biomarkers including sputum eosinophilic and neutrophilic count on serum level of periostin and eotaxin-2 in asthmatic patients were …