Immediate care is an essential nursing function to identify early deterioration in mental status. The nurse monitors the patient's mental status closely .Oxygen is administered if oxygen de-saturation occurs. The nurse monitors for fever or abdominal pain. This may be a signal the onset of bacterial peritonitis or other infection. Aim of the study was to investigate the immediate nursing care for hepatic encephalopathy patients' to reduce gastrointestinal complication on patient's outcome. Subject and methods descriptive research design was used to conduct this research. The sample of this study was consisted of 60 patients. Tools used in this study comprised three main tools. Tool 1:- patients assessment sheet. Tool 11:-fluid intake and| output and nutrition assessment. Tool 111:- Evaluation sheet. The main result:- Regarding West- haven criteria there was a significant decrease for the studied group from 1 st day and 2nd day. There were statistical significance differences between the two days. Regarding complete blood picture; WBC in the studied group showed that significant decrease on 2nd day. Fluid intake & output in the studied group showed that significant increase on 2nd day. Conclusion:- Applied immediate nursing care significant to reduce gastrointestinal complication in hepatic encephalopathy patients and improve the patient's outcome. Therefore, it is recommended to providing nutritional counseling for all patients with hepatic encephalopathy, continuing Educational Nursing Programmes to access the high quality of care. Keywords: Hepatic encephalopathy, immediate nursing care, patient's outcome