Background: Most asthmatic patients use their inhalers incorrectly; As a result, they are more vulnerable to poor clinical control and exacerbation. The study aim: was to evaluate the effect of different nursing educational methods (video, educational booklet, both booklet & video) about correct use of inhaler devices on the clinical improvement for asthmatic patients. Methods: Design of the study: Quiz-experimental design. Setting: chest department and chest diseases outpatient clinics at Assiut University Hospitals Sample: 80 asthmatic patients were divided into four groups, 20 patients for each. Tools: Tool I: patient assessment sheet, Tool II: Global Initiative for Asthma scale (GINA), 2019, and Tool III: nursing educational methods. Results: According to the Global Initiative for Asthma scale, in excess of half of the patients (60.0 %) in the routine nursing instructions, booklet, and video groups had partially asthma control, while the majority of patients (80.0%) in the video and booklet groups had well asthma control. Conclusions: The group of patients who received the video and the booklet had a statistically significant effect on improving the level of asthma control. Recommendation: All asthma patients should be given written and visual information about how to use inhalers devices correctly to minimize the complications arising from the incorrect use of inhalers.