Department Researches & Publications

Faculty of Pharmacy

Assiut University

Department of Pharmaceutical Analytical Chemistry

Research

Our research spans a wide range from basic chemical, analytical, and pharmaceutical studies. Much of this research is focused on three strategic Research Themes: Pharmaceutical analysis and quality control - Analysis of drugs in biological fluids and - Environmental monitoring. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones, analysis of drugs and compounds of pharmaceutical interest in pure form and in different formulations with the best possible sensitivity, accuracy and precision. Moreover, the basic and advanced studies that are done in the field of biological fluid analysis and environmental matrices. The Department has major national and international collaborative research projects and a significant output of research publications in high-ranking journals (More than 400 publications up to 2010). Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
51 HPTLC/MS and HPTLC/UV for monitoring of degradation behavior of some β-Lactam antibiotics mixtures under ambient storage conditions 2023
52 Bifunctional Fe(III) metal-organic framework: A highly sensitive “turn-off” fluorescent probe and a precursor of magnetite nanoparticles for potential water decontamination 2023
53 Development of sensitive spectrofluorometric approach based on formation of pyrrolidone derivative for determination of linagliptin through condensation reaction with ninhydrin and phenylacetaldehyde: Application to content uniformity and real plasma 2023
54 A novel mesna-based electrochemical sensor embellished with silver nanoparticles for ultrasensitive analysis of modafinil Human Plasma 2023
55 A selective dual quenching sensor (EY/BG@CDs) for simultaneous monitoring of gentamicin and ketorolac levels in plasma: a highly efficient platform that caters to the needs of therapeutic drug monitoring† 2023
56 A feasible HPTLC method for concurrent quantitation of allopurinol-montelukast co-therapy in plasma and evaluation of their hepatic and renal effects in rats: Analytical, biochemical, and histopathological study 2023
57 Development of a highly sensitive and eco‑friendly high‑performance thin‑layer chromatography approach for the determination of empagliflozin, pioglitazone, and rosuvastatin simultaneously in pharmaceutical preparations and different biological fluids 2023
58 Polypyrrole/carbon dot nanocomposite as an electrochemical biosensor for liquid biopsy analysis of tryptophan in the human serum of normal and breast cancer women 2023
59 Combined Experimental/Computational Aspects for the Molecular Interaction of Empagliflozin with Bovine Serum Albumin: Quantification, and Application to Human Plasma 2023
60 Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe† 2023