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Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
111 Synthesis, anti-inflammatory and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetone thiosemicarbazone cyclized derivatives as PLA-2 inhibitors 2015
112 Annonaceous Acetogenins as a new anticancer agent
2015
113 Cu (I) Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition (CuAAC): Synthesis of 17α-[1-(Substituted Phenyl)-1,2,3-Triazol-4-yl]-19-Nortestosterone-17β-yl Acetates Targeting Progestational and Antipro-Liferative Activities 2015
114 Lipases-catalyzed enantioselective kinetic resolution of alcohols 2015
115 Synthesis and In Vitro Evaluation of Ferutinol Aryl Esters for Estrogenic Activity and Affinity Toward Cannabinoid Receptors 2015
116 Cu (I) Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition (CuAAC): Synthesis of 17α-[1-(Substituted Phenyl)-1,2,3-Triazol-4-yl]-19-Nortestosterone-17β-yl Acetates Targeting Progestational and Antipro-Liferative Activities 2015
117 Lipases-catalyzed enantioselective kinetic resolution of alcohols 2015
118 Salting-out thin-layer chromatography and computational analysis of some oral hypoglycemic drugs 2014
119 Novel Non-Cyclooxygenase Inhibitory Derivatives of Naproxen for Colorectal Cancer Chemoprevention 2014
120 Some New NSAIDs Prodrugs: An Efficient Synthesis, Spectral Characterization and X-ray Crystal Structure Studies 2014