Phytochemical investigation of the aerial parts of Sanchezia nobilis Hook. family Acanthaceae has yielded matsutake alcohol (1-octen-3-ol) (1) and four matsutake alcohol glycosides identified as 3-O--glucopyranosyl-1-octen-3-ol (2), 3-O--glucopyranosyl-(16)--glucopyranosyl-1-octen-3-ol (3), 3-O--arabino-pyranosyl-(16)--glucopyran-osyl-1-octen-3-ol (4), and 3-O--arabino-pyranosyl-(16)--glucopyranosyl-(16)--glucopyranosyl-1-octen-3-ol (5). The structures of the isolated compounds were assigned on the basis of different techniques of NMR spectral analysis. Compounds 1–4 have been isolated here for the first time from the family Acanthaceae, while compound 5 is isolated here for the first time from a natural source.