Botryodiplodia theobromae Pat. belongs to the endophytic fungi that live within the tissues of medicinal plants and produce bioactive natural products. The endophyte was isolated from the leaves of Dracaena draco L. The LC–MS-based metabolite fingerprinting of the ethyl acetate extract of B. theobromae with antibacterial activity led to the identification of 13 metabolites pertaining to various classes: dipeptides (maculosin and L,L-cyclo(leucylprolyl), alkaloid (norharman), coumarin and isocoumarins (bergapten, meranzin and monocerin), sesquiterpene (dihydrocumambrin A), aldehyde (formyl indanone), fatty alcohol (halaminol A) and fatty acid amide (palmitoleamide, palmitamide, capsi-amide and oleamide). This study reports for the first time, the LC–MS and LC–MS/MS identification of 13 known bioactive metabolites from the antibacterial ethyl acetate extract of B. theobromae isolated from the leaves of D. draco L.
Research Department
Research Journal
Natural Product Research
Research Publisher
NULL
Research Rank
1
Research Vol
Vol. 29, No. 24
Research Website
http://dx.doi.org/10.1080/14786419.2015.1012715
Research Year
2015
Research Member
Research Abstract