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Meeting of the Council of the Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy that will be on Wednesday, March 4, 2026

God willing, The Pharmaceutical Analytical Chemistry Department Council will hold its regular monthly meeting No. (536) And that will be on Wednesday, March 4, 2026, at 12:00 PM 

 In the meetings Hall of the Department

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خبر عام

Scheduling of the Drug Design Lecture for Clinical Pharmacy Students (Semester 10) During the Month of Ramadan

It has been decided that the Drug Design lecture for Clinical Pharmacy students (Semester 10) will be held every Sunday at 1:00 p.m. at the Medicinal Chemistry Department Lecture Hall throughout the month of Ramadan.

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إعلانات الطلاب

Meeting of the Council of the Pharmaceutics Department, Faculty of This will take place on Monday, March 2, 2026, at 10:30 A.M

God willing, the meeting of the Pharmaceutics Department Board of the Faculty of Pharmacy No. (548), at the Faculty of Pharmacy, on Monday, March 2, 2026, at 10:30 A.M

in the department board on the third floor under the chairmanship of the Faculty to discuss the topics that we will inform you later.

 

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May God have mercy on him.

 

With deepest sorrow and heartfelt condolences

the Faculty of Pharmacy mourns the passing of
Prof. Dr. Mohamed Ali Attia
Emeritus Professor of Pharmaceutics,
husband of
Prof. Dr. Fawzia Habib
Emeritus Professor of Pharmaceutics.

May Allah grant the deceased His mercy and forgiveness,
and extend sincere condolences to the family.
The funeral prayer will be held after Friday prayer
at Omar Makram Mosque.

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Alizarin red S@ZIF-8 composite-modified carbon paste electrode: A novel sensitive sensor for the voltammetric determination of asenapine maleate in human plasma

Research Abstract

The development of a novel, highly sensitive electrochemical sensor for ASP based on an alizarin red S-functionalized zeolitic imidazolate framework-8 (ALZ@ZIF-8) nanocomposite. The nanocomposite was synthesized via a one-pot approach and fabricated on a carbon paste electrode (ALZ@ZIF-8/CPE). Its interaction with ASP was elucidated through density functional theory (DFT) calculations and electrochemical analysis, while its structure was confirmed using SEM, XRD, FT-IR, UV-Vis, and spectrofluorimetric techniques. Under optimized conditions, a square-wave voltammetric (SWV) method was developed and rigorously validated. The sensor demonstrated a wide linear range from 0.01 to 14.0 µM, with exceptional sub-micromolar sensitivity (detection limit: 3.45 nM; quantification limit: 10.46 nM). The method showed high accuracy (recoveries: 99.26–101.62%) and precision (relative standard deviation, RSD ≤ 1.01%). Successful application to spiked human plasma yielded recoveries ≥ 98.84% with RSDs ≤ 1.61%, confirming practical utility. This work presents the first application of the ALZ@ZIF-8 nanocomposite in analysis. The proposed sensor offers a promising and adaptable platform for the sensitive detection of ASP and other target molecules in complex biological media.

Research Authors
,Noha M Hosny, Antonio Frontera, Ibrahim A Darwish
Research Date
Research Journal
Microchimica Acta
Research Member
Research Pages
1-19
Research Publisher
Springer Nature
Research Rank
Q1
Research Vol
193
Research Website
https://doi.org/10.1007/s00604-026-07839-5
Research Year
2026
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