Do you have any questions? (088) 2080369 - 2345622 Pharmacy_QAAU@pharm.aun.edu.eg
God willing, the Pharmaceutical Organic Chemistry Department Council will hold its regular monthly meeting number (495) This is On Tuesday, June 3, 2025, at 11:00 AM
In the department council meeting room.
God willing, The Pharmacognosy Department Council will hold its regular monthly meeting number (58) will be held on Tuesday, June 3, 2025, at 10:00 AM.
In the department board meeting room.
God willing, The Pharmaceutical Analytical Chemistry Department Council will hold its regular monthly meeting number (527) this will take place on Monday, June 2, 2025, at 11:00 AM.
God willing, the meeting of the Pharmaceutics Department Board of the Faculty of Pharmacy No. (540) "This will take place on Monday, June 2, 2025. at ten o’clock in the morning
in the department board on the third floor under the chairmanship of the Faculty to discuss the topics that we will inform you later.
The sale of the Department of Pharmacognosy's farm products will take place on:
Monday, June 2, 2025
Tuesday, June 3, 2025
at 10:00 AM
At the sales outlet, Faculty of Pharmacy
Available Products and Prices:
|
Price |
Product |
|
5 EGP/kg |
Fresh Mint |
|
90 EGP/kg |
Dried coriander |
|
40 EGP |
Fenugreek |
Stevioside and rebaudioside A revealed anticancer effects against diversity of cancers, such as colon, breast and
liver cancers. Rebaudioside A can trigger apoptosis in cancer cells via activation of caspase-dependent pathway.
In this study, sodium alginate/poly(N-vinylpyrrolidone) as nano-carriers loaded with natural products rebaudioside A (R) and/or stevioside (S) were assessed for anticancer activities. The nanogel of structure R improved
cytotoxicity against MCF-7, HepG2, HCT116 and A549 cancers by 60.29 %, 53.45 %, 72.86% and 62.13%,
correspondingly. Additionally, the nanogel of structure S improved cytotoxicity against MCF-7, HepG2, HCT116
and A549 cancers by 63.96%, 53.41%, 70.59% and 52.88%, respectively. Furthermore, the nanogel for
mixture of R/S improved cytotoxicity against MCF-7, HepG2, HCT116 and A549 cancers by 78.86%, 54.75%,
74.10 % and 56.53%, correspondingly. Also, cytotoxic activities of structures R, S and R/S and their nanogels
exhibited low toxicity on VERO cells with IC50 = 30.90–46.50 μM and high selectivity against cancer cells.
Moreover, R/S (nanogel), R (nanogel) and S (nanogel) demonstrated the uppermost binding affinities with DNA
at reduced IC50 values of 31.50, 32.60, and 33.90 μM, respectively. In addition, they inhibited Topo-II activity
with remarkably low IC50 values of 0.95, 1.00, and 1.10 μM, respectively.
