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Pyrazoles and Pyrazolo[4,3-e]pyrrolo[1,2-a]pyrazines, I. Synthesis and Microbial Activity

مؤلف البحث
Abdel-Rahman Farghaly and Hussein El-Kashef
ملخص البحث

The synthesis of the title compounds was achieved using 1-phenyl-5-(pyrrol-1-yl)-1H-pyrazole-3-carboxylic acid azide as starting material. The latter compound was allowed to react with alcohols and amines to afford the corresponding carbamates and urea derivatives. Alkaline hydrolysis of the carbamates gave the corresponding amine, which was acylated and/or aroylated to give amide derivatives. These and the urea derivatives were subjected to cyclodehydration to give the title compounds. Antibacterial and antifungal activities were observed for several derivatives

قسم البحث
مجلة البحث
Monatshefte für Chemie
المشارك في البحث
الناشر
Springer Wien
تصنيف البحث
1
عدد البحث
Vol. 136, No. 2
سنة البحث
2005
صفحات البحث
pp. 371-376