Several thieno[2,3-b]quinolines 6a-i have been synthesized. These compounds were used as key intermediates in the synthesis of oxazino[4,5:4,5]thieno[2,3-b]quinoline 8, pyrimido[4,5:4,5]-thieno[2,3-b]quinolines 9-12, triazino[4,5:4,5]thieno[2,3-b] quinolines 14 and imidazo[4,5:4,5]-thieno[2,3-b]quinolines 17.