ملخص البحث
Oxidative stress induced hyperglycemia plays a central role in the pathogenesis of diabetes and its complications in most of the tissues. In the present study the protective roles of lipoic acid and n-acetylcysteine for the treatment of oxidative stress in alloxan-induced diabetic rabbits were studied. The obtained results concluded that lipoic acid or N-acetylcystiene my be hseful for the therapy of oxidative stress associated with hyperglycemia. The beneficial action seems to result mainly from direct scavenging of ROS and restoring glutathione redox state.
قسم البحث
مجلة البحث
Assiut J of Zoology
المشارك في البحث
الناشر
Faculty of Science, Assiut Univ.
تصنيف البحث
3
عدد البحث
Special Publ. N0 2
سنة البحث
2009
صفحات البحث
181-209