ملخص البحث
Histone post-translational modifications (PTMs) regulate numerous cellular processes, including gene transcription, cell division, and DNA damage repair. Most histone PTMs affect the recruitment or exclusion of reader proteins from chromatin. Here, we present a protocol to measure affinity and interaction kinetics between histone peptides and the recombinant protein using Bio-layer interferometry.
تاريخ البحث
قسم البحث
مجلة البحث
Bio-protocol
المشارك في البحث
عدد البحث
8
سنة البحث
2018
صفحات البحث
e3012-e3012