Unintentional environmental effects brought on by insecticides
encourage the creation of safer substitutes. A very polyphagous
migrating lepidopteran pest species in Africa called S. Frugiperda
causes terrible damage. In the current paper, treatment of 4-
acetylphenyl 4-methylbenzenesulfonate with different aromatic
aldehydes in the presence of NaOH afforded benzylideneacetophenones.
The structure of the newly prepared compounds
were proved by different spectroscopic techniques such as IR,
1H-NMR, 13C NMR, and elemental analysis. We looked at the
association between contact with S. frugiperda and stricture
reaction to examine their harmful effect. Additionally, S.
frugiperda was used for testing the newly created compounds
for their ability to kill insects. The majority of substances have
been proven to be effective and promising. It has been found
that 4-[3-(4-Methylphenyl)prop-2-enoyl]phenyl-4-methyl benzenesulfonate
(4) was the most active with an LC50=3.46 mg/L of
2nd instar larvae and LC50=9.45 mg/L of 4th instar larvae.
Moreover, some of biological and histopathological aspects of
the synthesized products were investigated under laboratory
conditions.