Neoplastic diseases of the donkey are rarely documen¬ted in present literature. The four cases described in this article were selected from a large number of oncologic cases in this species and represent common presentati¬ons and treatments. In all the four donkeys described here, the tumors were occluding body orifices. Histo¬pathological examination revealed a fibroma in two ca¬ses, a fibromyxoma in one case, and a fibropapilloma in another case. Surgical treatment is described.