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MMP-9 Expression in Normal Rabbit Chondrocytes

مؤلف البحث
Hanan H Abd-Elhafeez, Basma Kamal, Abeera M El-Sayed, Soha A Soliman
ملخص البحث

Chondrocytes regulate anabolic and catabolic processes to maintain the extracellular matrix components. Catabolic activities depend on the proteolytic action of the matrix -degrading enzymes including ADAMTS (A disintegrin and metalloproteinases) and MMP (Matrix Metalloproteinase). The current study explored the distribution of MMP-9 in normal articular cartilages of the embryos rabbit. Articular cartilage has grown by appositional growth that the perichondrial stem cells differentiate into chondrocytes. MMP-9 positive perichondrial stem cells or chondroblasts and early chondrocytes. Mature chondrocytes exhibited weak immunoaffinity for MMP-9. In conclusion, MMP-9 was essential during chondrocytes growth. The current study alludes to the potential role of MMP-9 during the growth of the articular cartilage.

مجلة البحث
Cytology and Histology International Journal, Volume 5 Issue 1 Pages 1-9
المشارك في البحث
الناشر
https://medwinpublishers.com/
عدد البحث
Volume 5 Issue 1
موقع البحث
https://www.semanticscholar.org/paper/MMP-9-Expression-in-Normal-Rabbit-Chondrocytes-Soliman/393e99fe864cacf4a1068faf4fac6fec4e0bb7c3
سنة البحث
Received Date: April 08, 2021 Published Date: April 29, 2021
صفحات البحث
Pages 1-9