The main aim of this paper is to define and study of the Chebyshev matrix polynomials. An explicit representation, a three-term matrix recurrence relations for the Chebyshev matrix polynomials are given. These polynomials appear as finite series solutions of second order matrix differential equations. The expansion Chebyshev matrix polynomials in series of Hermite matrix polynomials and the Christoffel formula of summation are established.