Ethyl 5-cyano-1,6-dihydro-2-methyl-4-styryl-6-thioxonicotinate, its piperidinium pyridine-6-thiolate and 3-
acetyl-5-cyano-1,6-dihydro-2-methyl-4-styryl-6-thioxopyridine were used as starting materials for synthesizing
novel series of S-substituted methylthiopyridine-5-carbonitriles and thieno[2,3-b]pyridines with expected
biological activity. Also, some novel thieno[2,3-c][2,7]naphthyridinones were synthesized. Moreover, 1,7-
diamino-8,9-dihydro-5-methyl-8-phenyl-3H-pyrazolo[3,4-c][2,7]naphthyridine-6(7H)-one was synthesized by
heating ethyl 5-cyano-1,6-dihydro-2-methyl-4-styryl-6-thioxonicotinate with hydrazine hydrate 99% under
neat conditions. The obtained promising aminopyrazolo[3,4-c][2,7]naphthyridine-6(7H)-one was used as a
precursor to get other novel derivatives with expected biological and medicinal importance. Structures of all
new compounds were elucidated by elemental and spectral analysis.
ملخص البحث
تاريخ البحث
قسم البحث
مجلة البحث
ARKIVOC
المشارك في البحث
سنة البحث
2024