Crystal structure and Hirshfeld surface analysis of (3S,3aR,6aS )-3-(1,3-diphenyl-1H-pyrazol-4-yl)-5-(4-methoxyphenyl)- 2-phenyl-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[3,4- d ][1,2]oxazole-4,6-dione

Faculty Of Science

Assiut University

Crystal structure and Hirshfeld surface analysis of
(3S,3aR,6aS )-3-(1,3-diphenyl-1H-pyrazol-4-yl)-5-(4-methoxyphenyl)-
2-phenyl-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[3,4-
d ][1,2]oxazole-4,6-dione

Research Authors
Shaaban K. Mohamed, Awad I. Said, Joel T. Mague, Talaat I. El-Emary,
Mehmet Akkurt and Sahar M. I. Elgarhy
Research Abstract

Oxazole scaffold compounds currently find application in
medicinal drugs such as Aleglitazar (antidiabetic), Ditazole
(platelets aggregation inhibitor), Mubritinib (tyrosine kinase
inhibitor), and Oxaprozin (COX-2 inhibitor) (Kakkar et al.,
2018). In addition they show anti-microbial (Tomi et al., 2015)
and anti-cancer (Liu et al., 2009) activity.In this context, we
determined the crystal structure of the title compound

Research Department
Department of chemistry
Research Journal
Acta Cryst.Acta Cryst.
Research Member
Talaat Ibrahim Ali El-Emary
Research Publisher
IUCr Journals CRYSTALLOGRAPHY JOURNALS ONLINE
Research Rank
1
Research Vol
77
Research Website
research communications, https://doi.org/10.1107/S2056989021002358
Research Year
2021
Research Pages
356–359