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Cytotoxic and hemotoxic effects of silver nanoparticles on the African
Catfish, Clarias gariepinus (Burchell, 1822)

Research Authors
Imam A. Mekkawy, Usama M. Mahmoud, Mervat N. Hana, Alaa El-Din H. Sayed⁎
Research Abstract

The present study investigates the hemotoxic and cytotoxic impacts of two acute doses of silver nanoparticles
(AgNPs) on the African catfish, Clarias garepinus in comparison to the impact of AgNO3 and the control fish.
AgNPs-induced impacts were recorded on some biological and hematological indices of that species on the bases
of their size (20 and 40 nm) and concentration (10 and 100 µg) but no significant interaction. AgNO3 had very
low impact on these indices in comparison to AgNPs. Recovery period for 15 days was found to be valid to
remove AgNPs and AgNO3 toxicity for most indices. The condition factor exhibited stability under stress whereas
the hepatosomatic index was more sensitive to AgNPs. The AgNPs-induced hematological changes recorded were
corresponding with different blood cell alterations which increased in frequency from the control and AgNO3 to
40 nm/100 µg; such blood cell alterations disappeared to great extent after recovery period of 15-days in a
reverse order

Research Department
Research Journal
Ecotoxicology and Environmental Safety
Research Publisher
NULL
Research Rank
1
Research Vol
Vol. 171
Research Website
NULL
Research Year
2019
Research Pages
pp. 638–646