Research Abstract
The synthesis of indeno[2,1-e]pyrazolo[3,4-b]pyrazin-5-onewas achieved by intramolecular FriedeleCrafts
reaction of the acid chloride 3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b] pyrazine-5-carboxylic acid chloride
(4) using AlCl3 in boiling CS2. Compound 4 proved to be a versatile compound for the synthesis of several
Indenopyrazolopyrazinone derivatives. The antibacterial and antifungal activities of selected derivatives
were evaluated.
Research Department
Research Journal
European Journal of Medicinal Chemistry
Research Member
Research Rank
1
Research Vol
Vol. 62
Research Year
2013
Research Pages
PP. 478-485