The effect of electrical currents 3, 5 and 10 mA as well as a combination of lectrical currents of 5 and 10 mA and 1.8 mM Sodium chloride solution on glycogen, nonglycogen polysaccharides and total protein contents of hind limb regeneration in a climactic metamorphic stage (57( of the Egyptian toad, Bufo regularis Reuss was studied after amputation at distal third of the thigh and mid shank levels. The depletion of glycogen, nonglycogen polysaccharides and total proteins in the various tissues of limb regenerates was observed after five days of treatment whereas after fifteen days there was an increase in the amount of these substances. It was suggested that the increase in polysaccharides and proteins could be due to the restoration od aerobic cellular respiration and the relatively slow rate of building up of new cells.