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Synthesis of Some Phenylazopyridothienopyrimidines

Research Authors
Adel M. Kamal El-Dean
Research Abstract

2-Mercapto-S-phenylazo-4,6-dimethylpyridine-3-carbonitr(i3l)e reacts with halocompounds to give Salkylated
derivatives (421-h) which upon treatment with sod. ethoxide in ethanol, the thienopyridines
(5a-h) was obtained. Compound (5) converted into pyridothienopyrimidines (6a-e) or (7a,b) boiling
with triethyl orthoformate or acetic anhydride. Also it can be converted into pyridothienotriazine (8ad)
by treating with nitrous acid. Chloropyridothienopyrimidine (IOa,b) was obtained by refluxing compound 6a or 7a with POCI3.

Research Department
Research Journal
Phosphorus. Sulfur. and silicon
Research Publisher
Gordon and Breach Science Publishers SA
Research Rank
1
Research Vol
90
Research Website
DOI: 10.1080/10426509408016389
Research Year
1994
Research Pages
pp. 85-93