Two-dimensional nanomaterials such as graphene nanosheets and molybdenum disulfide nanoflakes were easily hybridized with spinel Mn₃O₄ in a single deposition process at low temperature by a facile kinetic spray approach under low vacuum conditions using a nano-particle deposition system. The heterostructured Mn₃O₄–2D hybrid nanocomposites (NCs) were utilized to enhance the reaction kinetics of oxygen evolution. Hybrid NCs of Mn₃O₄ with MoS₂ and graphene showed nanoflakes and nanosheet morphologies, respectively. The synergy improvement in nanocomposites of Mn₃O₄-graphene nanosheets and Mn₃O₄₋MoS₂ nanoflakes was examined by x-ray photoemission spectroscopy and analysis of Raman spectra that results in a decrease in OER overpotential to 289 mV at 10 mA⋅cm⁻² for Mn₃O₄-graphene nanosheets and 295 mV for Mn₃O₄₋MoS₂ nanoflakes. The estimated Tafel slope strongly decreased from 88 mV⋅dec⁻¹of pure Mn₃O₄ nanorods to around 44 mV⋅dec⁻¹ for hybrid NCs. This behavior indicates improved charge transfer kinetics due to the decrease in charge transfer resistance. Furthermore, all fabricated nanostructure electrocatalysts exhibited very good stability for prolonged galvanostatic polarization up to 50 h.