The kinetics of platinum(IV) oxidation of cadaverine (CAD) in perchloric acid medium was studied at a constant ionic strength of 2.0 mol dm-3 and at 25°C. The oxidation reaction was followed spectrophotometrically. The reaction exhibited a first order kinetics in [PtIV] and less than unit order dependences with respect to [CAD] and [H+ ]. Increasing ionic strength and dielectric constant decreased the oxidation rate. The final oxidation products of cadaverine were identified as 5-aminopentanal and ammonia. The oxidation mechanism was proposed and the appropriate rate-law expression was deduced. The activation parameters of the second order rate constant were evaluated and discussed.