The kinetics of oxidation of N, N-dimethyl-N’-(pyridin-2-yl) formamidine (Py-F) by cerium(IV) was studied spectrophotometrically in aqueous perchloric acid solutions at a constant ionic strength of 1.0 mol dm-3 and at 20°C. The reaction showed first order dependence with respect to [Ce(IV)] and less than unit order with respect to [Py-F]. The reaction exhibited negative fractional-first order kinetics with respect to [H+ ]. The rate of reaction was not significantly affected by variation of either ionic strength or dielectric constant of the reaction medium. Addition of cerium(III) product did not affect the reaction rate. A suitable mechanistic scheme for the oxidation reaction has been proposed. The final oxidation products were identified as 2-aminopyridine, dimethylamine and carbon dioxide. The activation parameters have been evaluated and discussed. The rate law associated with the reaction mechanism was derived.