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Novel synthesis and reactions of pyrazolylsubstituted
tetrahydrothieno[2,3-c]isoquinoline
derivatives

Research Authors
Remon M. Zaki, Adel M. Kamal El Dean, Maisa I. Abd El Monem, Mohamed A. Seddik
Research Abstract

Treatment of isoquinolinecarboxamide 4a
with triethyl orthoformate, chloroacetyl chloride or
carbon disulfide afforded the pyrimidinone 7, oxopyrimidinethione
12 and chloromethylpyrimidinone 18,
respectively. These products were used as versatile starting
materials for synthesis of other heterocyclic compounds.
The heterocyclic hydrazide 6 was also obtained.

Research Department
Research Journal
Heterocycl. Commun.
Research Publisher
NULL
Research Rank
1
Research Vol
Vol. 22, No. 2
Research Website
NULL
Research Year
2016
Research Pages
pp. 103–109