Pb (II) and Hg (II) ions were reacted in aqueous solution with two tridentate thiosemicarbazones, resulting in four complexes {[Pb(L1)2] 1, [Pb(L2)2] 2, [Hg(L1)2] 3 and [Hg(L2)2] 4; HL1 = 4-(4-nitrophenyl)-1-((pyridin-2-yl)methylene)thiosemicarbazide and HL2 = 4-(2-chlorophenyl)-1-((pyridin-2-yl)methylene)thiosemicarbazide}. The solid-state structures of complexes 2 and 3 were determined by X-ray crystallography, which also confirmed the monobasic tridentate NNS nature of the ligands, and the octahedral coordination geometry around the metal centers. Complexes 1-4 exhibited high antifungal activity against the pathogen Cladosporium sphaerospermum; all four complexes giving rise to a reduction in the fungal dry mass and sugar consumption. Complexes 2 and 4 that inhibited Cladosporium sphaerospermum growth at the concentration of 1.8 mM are more efficient inhibitors than the free ligand and metal ions. Further, the complexes gave varied values of the fungal total antioxidants (TA), superoxide dismutase (SOD) and catalase (CAT) activities dependent on their concentrations.
Research Abstract
Research Date
Research Department
Research Journal
Applied Organometallic Chemistry
Research Member
Research Publisher
Wiley
Research Rank
International
Research Vol
36(8)
Research Website
https://onlinelibrary.wiley.com/doi/abs/10.1002/aoc.6798
Research Year
2022
Research Pages
e6798