Polysaccharides are widely used for several applications, including biomedical science. They can be used in tablet formulation, coating biomedical implants, dental implants, tumor-targeting implants and regenerative medicine, bone and tissue engineering, and drug delivery. They are biocompatible, exhibit low toxicity, and require low cost. Several polysaccharides can be extracted from plants, animals, and microorganisms. Polysaccharides exhibit high performance as implants. Drug loading or release using polysaccharides is optimal compared to conventional polymers. This book chapter summarized the applications of polysaccharides for biomedical implants. It can be a brief introduction for the researchers and scientists looking for biomedical implants using polysaccharides.