The pesticides have different adverse impacts on different life stages of fish species with attempts to
use dietary antioxidants to counteract their effects. So, the present study investigated the potential
protective effects of vitamin E (50 mg/kg BW), tomato paste (in terms of 9 mg lycopene/kg BW) and their
combination versus atrazine-induced changes in Clarias gariepinus. This species were exposed to
sublethal doses of atrazine of 1.7 and 3.4 mg/L for 15 and 30 days. Atrazine significantly (P<0.05)
induced free radicals in serum constituents. It caused a significant (P<0.05) increase in serum glucose,
mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and lipid peroxidation in liver.
Addition of vitamin E and/or tomato paste to the diet of atrazine-treated fish improved the serum
glucose, MCV, MCH and LPO levels in comparison to control fish. On the other hand, atrazine
significantly (P<0.05) led to decline in serum total protein, total lipid, blood hemoglobin, total
erythrocytes count, packed cell volume, and mean corpuscular hemoglobin concentration.These
atrazine-induced parameters were improved with the dietary supplemented tomato paste and/or vitamin
E.