In the present study the protective role of quince leaf extract against the adverse impacts of ultraviolet
radiation-A (UVA) on some tissues of Clarias gariepinus (Burchell, 1822) was considered. Fishes were classified
into four groups: control, UVR-treated group (for 3 days/for 3 h/day), UVR-treated group (for
3 days/for 3 h/day) with adding 10 ml of quince extract, and UVR-treated group (for 3 days/for 3 h/day)
with adding 20 ml of quince leaf extract. Blood smears and sections of the liver, and skin were processed
routinely for H & E paraffin embedding technique. Some UVA-induced malformations were recorded in
the red blood cells including crenated cells (Cr), Acanthocytes (Ac), tear drop-like cells (Tr) and sickle cells
(Sk). Also, UVA-induced disorganization of the normal architecture of hepatic tissues with lipidosis was
evident. Hypertrophy and vacuolated club cells were recorded in skin exposed to UVA. In conclusion,
quince leaf extract has a valuable antioxidant protective role to prevent and/or repair the histopathological
changes induced by UVA.