Skip to main content

Synthesis and Biological Activity of some New Benzimidazolylazetidin-2-one and –Thiazolidin-4-ones

Research Authors
A.E. Abdel-Rahman, A.M. Mahmoud, G.M. El-Naggar and H.A. El-Sherief
Research Abstract

Arylidene-2-aminobenzimidazoles (1) were prepared by condensation of 2-aminobenzimidazole with aromatic aldehydes. Cyclocondensation of mercaptoacetic acid, chloracetylchloride and phthaloyl glycyl chloride on 1 giving the corresponding 4-thiazolidinones (2) and azetidinones (3 and 4) respectively, in good yields. The biological activities of the prepared compounds were screened against several strains of bacteria.

Research Department
Research Journal
Bull. Fac. Sci., Assuit Univ. 11(1)B p-p. 48 (1982). & Pharmazie
Research Rank
2
Research Vol
Vol. 38, No. 9
Research Year
1983
Research Pages
pp. 589-590