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Synthesis of Morphlinotetrahydrothieno[2,3-c]isoquinolines

Research Authors
Adel M. Kamal El-Dean, Shaban M. Radwan and Remon M. Zaki
Research Abstract

1-Morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (2) was synthesized from 3-amino-
1-thioxo-5,6,7,8-tetrahydro-1H-isothiochromene-4-carbonitrile (1) and used as starting material to synthesize many thienotetrahydroisoquinolines (4),which in turn were used in the synthesis of many pyrimidothienotetrahydroisoquinolines.

Research Department
Research Journal
Journal of the Chinese Chemical Society
Research Publisher
Chinese Chemical Society
Research Rank
1
Research Vol
55
Research Year
2008
Research Pages
1290-1299