The present study aims to evaluate the role of TQ on the oxidative damage induced by ACR in rat
testes. The administration of ACR resulted in elevation in testes MDA and NO levels and significant reduction in the level of GSH and the activity of SOD and CAT. Also, plasma testosterone was significantly elevated in ACR-treated rats as compared with negative control. These biochemical changes were associated with congestion and interstitial edema,necrosis, calcification and degeneration of spermatogenic cells and formation of spermatid gaint cells. Co-treatment with TQ ameliorates these biochemical and histological changes. In conclusion, supplementation with TQ as antioxidant
may offer protection against ACR induced testicular
toxicity.
Research Abstract
Research Department
Research Journal
The Journal of Free Radicals and Antioxidants. Photon
Research Member
Research Rank
1
Research Vol
142
Research Website
https://sites.google.com/site/photonfoundationorganization/home/the-journal-of-free-radicals-and-antioxidants
Research Year
2014
Research Pages
407-414